Apply a few drops to face in the AM and PM before creams. A tingling sensation can be expected after application. If the sensation is too strong to tolerate, the formula can be mixed with other creams or serums of your preference before each application to reduce the strength. If irritation occurs, cease use and consult a physician. Use only as directed on unbroken skin. Patch testing prior to use is advised. Refer to our in-depth guide to patch testing. Keep out of reach of children.